教授、博士生导师
单分子生物物理，基于纳米孔器件的单分子生物传感器，具有临床检测功能的单分子医疗诊断.
黄硕教授长期聚焦于开发具备仿生学概念的单分子纳米孔生物传感器相关的新仪器与新技术，以及基于纳米孔的单分子显微成像技术。目前已于国际权威期刊Nature Methods，Nature Nanotechnology，Nature Communications，Journal of the American Chemical Society, Science Advances，Angewandte Chemie International Edition, ACS Nano, Nano Letters等期刊发表论文若干。 其中以第一作者发表Nature Nanotechnology 2篇，并入选2010年12月刊封面；以唯一通讯作者发表Nature Methods 1篇, Nature Nanotechnology 2篇，并入选2022年9月刊封面。
1.Wang, K.#; Zhang, S.#; Zhou, X.#; Yang, X.; Li, X.; Wang, Y.; Fan, P.; Xiao, Y.; Sun, W.; Zhang, P.; Li, W.; Huang, S.*; Unambiguous discrimination of all 20 proteinogenic amino acids and their modifications by nanopore. Nature Methods 2024, 21 (1), 92-101.
2.Sun, W.#; Xiao, Y.#; Wang, K.#; Zhang, S.; Yao, L.; Li, T.; Cheng, B.; Zhang, P.; Huang, S.*, Nanopore discrimination of rare earth elements. Nature Nanotechnology 2025, https://doi.org/10.1038/s41565-025-01864-w.
3.Wang, Y.#; Zhang, S. #; Jia, W. #; Fan, P.; Wang, L.; Li, X.; Chen, J.; Cao, Z.; Du, X.; Liu, Y.; Wang, K.; Hu, C.; Zhang, J.; Hu, J., Zhang, P.; Chen, H.-Y.; Huang, S.*, Identification of nucleoside monophosphates and their epigenetic modifications using an engineered nanopore. Nature Nanotechnology 2022, 17 (9), 976-983.
4.Liu, Y.#; Zhang, S.#; Wang, Y.; Wang, L.; Cao, Z.; Sun, W.; Fan, P.; Zhang, P.; Chen, H.-Y.; Huang, S.*, Nanopore identification of alditol epimers and their application in rapid analysis of alditol-containing drinks and healthcare products. Journal of the American Chemical Society 2022,144(30), 13717–13728
5.Liu, Y.; Wang, K.; Wang, Y.; Yan, S.; Du, X.; Zhang, P.; Chen, H.-Y.; Huang, S.*, Machine Learning assisted simultaneous structural profiling of differently charged proteins in a Mycobacterium smegmatis porin A (MspA) electroosmotic trap. Journal of the American Chemical Society 2022,144(2), 757–768
6.Zhang, S.#; Cao, Z. #; Fan, P. #; Sun, W.; Xiao, Y.; Zhang, P.; Wang, Y.*; Huang, S.*, Discrimination of Disaccharide Isomers of Different Glycosidic Linkages Using a Modified MspA Nanopore. Angewandte Chemie International Edition 2024, e202316766.
7.Zhang, S.#; Cao, Z.#; Fan, P.#; Wang, Y.; Jia, W.; Wang, L.; Wang, K.; Liu, Y.; Du, X.; Hu, C.; Zhang, P.; Chen, H.-Y.; Huang, S.*, A Nanopore-Based Saccharide Sensor. Angewandte Chemie International Edition 2022，61(33):e202203769
8.Fan, P.; Li, K.; Li, T.; Zhang, P. K.; Huang, S.*, Nanopore signatures of major alcoholic beverages, Matter 2025, 8(3),101931.
9.Fan, P.#; Cao, Z.#; Zhang, S.#; Wang, Y.; Xiao, Y.; Jia, W.; Zhang, P.; Huang, S.*, Nanopore analysis of cis-diols in fruits. Nature Communications 2024,15 (1), 1969
10.Fan, P.#; Zhang, S.#; Wang, Y.; Li, T.; Zhang, H.; Zhang, P.; Huang, S.*, Nanopore analysis of salvianolic acids in herbal medicines. Nature Communications 2024,15 (1), 1970
