邹秉杰

图片1.png

邹秉杰

 副研究员

                 

 
 
 
 
研究方向
                     

主要从事核酸检测、疾病分子诊断与单细胞分析新方法研究。

             

个人简历
                     

邹秉杰, 1983 年3 月出生。2005年获得中国药科大学生物工程专业学士学位, 2008年获得中国药科大学微生物与生化药学硕士学位, 2011年获得中国药科大学微生物与生化药学理学博士学位。2012年3月进入东部战区总医院临床药学科做博士后(原南京军区南京总医院药理科);2014年赴日本日立制作所中央研究所进行短期进修,学习单细胞分析技术;2018年到澳大利亚莫纳什大学药物科学研究所做1年访问学者。2014 年至今为东部战区总医院临床药学科特聘文员。为江苏省杰出青年基金、江苏省“333”人才、江苏省“六大人才高峰”、江苏省医学青年重点人才项目获得者。现任中国药理学会分析药理学专业委员会第一届委员会副秘书长。

             

科研
                     

主持国家自然科学基金等7项国家及省部级课题,在Angew Chem Int Ed、Chem Sci、Genome Bio、Clin Chem等杂志发表论文48篇,先后获得过教育部科技进步一等奖(第四)1项、江苏省医学新技术引进二等奖(第一)1项及江苏省科技进步三等奖(第二)1项。

                         
主要论著
                     

1.Shu Xu, Shasha Cao, Bingjie Zou (co-fist authors), Yunyun Yue, Chun Gu, Xin Chen, Pei Wang, Xiaohua Dong, Zheng Xiang, Kai Li, Minsheng Zhu*, Qingshun Zhao* and Guohua Zhou*. An alternative novel tool for DNA editing without target sequence limitation: the structure-guided nuclease. Genome Bio. 2016, 17:186. (IF=13.21) 

2.Bingjie Zou, Yinjiao Ma, Haiping Wu and Guohua Zhou. Ultrasensitive DNA detection by cascade enzymatic signal amplification based on Afu flap endonuclease coupled with nicking endonuclease. Angew Chem Int Ed. 2011, 50: 7395-7398. (IF=12.1)

3.Yunlong Liu, Haiping Wu, Qiang Zhou, Qinxin Song, Jianzhong Rui, Xiaoxiang Guan, Guohua Zhou* and Bingjie Zou*, Controllable extension of hairpin-structured flaps to allow low-background cascade invasive reaction for sensitive DNA logic sensor of mutation detection, Chem Sci, 2018, 9: 1666-1673. (IF=9.06)

4.Jianping Wang, Bingjie Zou(co-fist authors), Yinjiao Ma, Xueping Ma, Nan Sheng, Jianzhong Rui, Yang Shao, Guohua Zhou*. Closed-tube PCR with nested serial invasion probe visualization using gold nanoparticles. Clin Chem. 2017, 63 (4): 852-860. (IF=8.64)

5.Yunlong Liu, Haiping Wu, Qiang Zhou, Qinxin Song, Jianzhong Rui, Bingjie Zou*, Guohua Zhou*. Digital quantification of gene methylation in stool DNA by emulsion-PCR coupled with hydrogel immobilized bead-array. Biosens Bioelectron. 2017, 92: 596-601. (IF=8.17)

6.Yan Lu, Xueping Ma, Jianping Wang, Nan Sheng, Tianhui Dong, Qinxin Song, Jianzhong Rui, Bingjie Zou*, Guohua Zhoua*. Visualized detection of single-Base difference in multiplexed loop-mediated isothermal amplification amplicons by invasive reaction coupled with oligonucleotide probe-modified gold nanoparticles. Biosens Bioelectron. 2017, 90: 388-393.  (IF=8.17) 

7.Bingjie Zou, Xiaomei Cao, Haiping Wu, Qinxin Song, Jianping Wang, Tomoharu Kajiyama, Hideki Kambara and Guohua Zhou. Sensitive and Specific Colorimetric DNA Detection by Invasive Reaction Coupled with Nicking Endonuclease-assisted Nanoparticles Amplification. Biosens Bioelectron. 2015, 66: 50-54. (IF=8.17)

8.Zhiyao Chen, Liyan Miao, Yunlong Liu, Tianhui Dong, Xueping Ma, Xiaoxiang Guan, Guohua Zhou * and Bingjie Zou*. A universal genotyping–microarray constructed by ligating a universal fluorescence-probe with SNP-encoded flaps cleaved from multiplex invasive reactions. Chem Commun. 2017, 53: 12922-25. (IF=6.29)

9.Bingjie Zou, Qinxin Song, Jianping Wang, Yunlong Liu and Guohua Zhou. Invasive Reaction Assisted Strand-displacement Signal Amplification for Sensitive DNA Detection. Chem Commun. 2014, 50(89): 13722-13724. (IF=6.29)

                 

联系方式
                     

Tel: 025-80860196

Email: zbj523@163.com