闵乾昊

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闵乾昊

(副教授) 

 
 
 
 
研究方向
 

基于纳米材料的生物分离、质谱分析、药物可控递送研究

 

个人简历
 
2003.09-2007.07  南京大学化学化工学院,化学学士
2007.09-2012.03  南京大学化学化工学院,分析化学博士
2012.04-2015.03  南京大学化学化工学院,助理研究员
2013.12-2014.12  美国斯坦福大学化学系,访问学者
2015.04-2015.08  南京大学化学化工学院,副研究员
2015.09至今   南京大学化学化工学院,副教授

 

科研
 

致力于选择性纳米探针的开发,通过有效整合纳米材料的理化特性和生物分子的识别功能,设计与构筑分子标志物响应性功能纳米探针,结合质谱分析、光学显微成像等分析技术,实现细胞过程中生物活性分子的监测、药物的精准递送与肿瘤的靶向治疗,为细胞过程的分子机制研究与肿瘤治疗策略的开发提供依据。2016年获国家自然科学基金优秀青年科学基金项目资助。在J. Am. Chem. Soc.,Angew. Chem. Int. Ed.,ACS Nano,Anal. Chem.等期刊上发表论文20余篇。

 

主要论著
 
1.    Z. Chen, J. Li, X. Chen, J. Cao, J. Zhang, Q. Min*, J.-J. Zhu*, Single gold@silvernanoprobes for real-time tracing the entire autophagy process at single-cell level. J. Am. Chem. Soc.137(5): 1903-1908 (2015) 
2.    P. Zhang, F. Cheng, R. Zhou, J. Cao, J. Li, C. Burda, Q. Min*, J.-J. Zhu*, DNA-Hybrid-Gated Multifunctional Mesoporous Silica Nanocarriers for Dual-Targeted and MicroRNA-Responsive Controlled Drug Delivery. Angew. Chem. Int. Ed.53(9): 2371-2375 (2014)
3.   P. Zhang, C. Wang, J. Zhao, A. Xiao, Q. Shen, L. Li, J. Li, J. Zhang, Q. Min*, J. Chen*, H. Chen, J.-J. Zhu*, Near Infrared-Guided Smart Nanocarriers for MicroRNA-Controlled Release of Doxorubicin/siRNA with Intracellular ATP as Fuel, ACS Nano, 10(3), 3637-3647 (2016)
4.    P. Zhang, Z. He, C. Wang, J. Chen, J. Zhao, X. Zhu, C.-Z. Li, Q. Min*, J.-J. Zhu*, In Situ Amplification of Intracellular MicroRNA with MNAzymeNanodevices for Multiplexed Imaging, Logic Operation, and Controlled Drug Release. ACS Nano 9(1): 789-798 (2015)
5. H. Xu, M. Liu, X. Huang, Q. Min*, J.-J. Zhu, Multiplexed Quantitative MALDI MS Approach for Assessing Activity and Inhibition of Protein Kinases Based on PostenrichmentDephosphorylation of Phosphopeptides by Metal-Organic Framework-Templated Porous CeO2, Anal. Chem., 90(16): 9859-9867 (2018)
6. T. Liang, Z. Yao, J. Ding, Q. Min*, L. Jiang*, J.-J. Zhu, Cascaded Aptamers-Governed Multistage Drug-Delivery System Based on Biodegradable Envelope-Type Nanovehicle for Targeted Therapy of HER2-Overexpressing Breast Cancer, ACS Appl. Mater. Interfaces, 10(40): 34050-34059 (2018)
7. J. Ding, T. Liang, Q. Min*, L. Jiang*, J.-J. Zhu, 'Stealth and Fully-Laden' Drug Carriers: Self-Assembled Nanogels Encapsulated with Epigallocatechin Gallate and siRNA for Drug-Resistant Breast Cancer Therapy, ACS Appl. Mater. Interfaces, 10(12): 9938-9948 (2018)
8. F. Zheng, P. Zhang, Y. Xi, K. Huang, Q. Min*, J.-J. Zhu*, Peptide-mediated core/satellite/shell multifunctional nanovehicles for precise imaging of cathepsin B activity and dual-enzyme controlled drug release, NPG Asia Mater., 9: e366 (2017)

 

联系方式
 
Email: minqianhao@nju.edu.cn
办公电话:025-89681977